Many diseases, such as heart disease and cancer, have both genetic and environmental components
Little is understood about the genetic contribution to most multifactorial diseases
Slide 85
Genetic counselors can provide information to prospective parents concerned about a family history for a specific disease
Slide 86
Using family histories, genetic counselors help couples determine the odds that their children will have genetic disorders
Slide 87
For a growing number of diseases, tests are available that identify carriers and help define the odds more accurately
Slide 88
In amniocentesis, the liquid that bathes the fetus is removed and tested
In chorionic villus sampling (CVS), a sample of the placenta is removed and tested
Other techniques, such as ultrasound and fetoscopy, allow fetal health to be assessed visually in utero
Video: Ultrasound of Human Fetus I
Slide 89
Fig. 14-18
Amniotic fluid
withdrawn
Fetus
Placenta
Uterus
Cervix
Centrifugation
Fluid
Fetal
cells
Several
hours
Several
weeks
Several
weeks
(a) Amniocentesis
(b) Chorionic villus sampling (CVS)
Several
hours
Several
hours
Fetal
cells
Bio-
chemical
tests
Karyotyping
Placenta
Chorionic
villi
Fetus
Suction tube
inserted
through
cervix
Slide 90
Fig. 14-18a
Fetus
Amniotic fluid
withdrawn
Placenta
Uterus
Cervix
Centrifugation
Fluid
Fetal
cells
Several
hours
Several
weeks
Several
weeks
Bio-
chemical
tests
Karyotyping
(a) Amniocentesis
Slide 91
Fig. 14-18b
(b) Chorionic villus sampling (CVS)
Bio-
chemical
tests
Placenta
Chorionic
villi
Fetus
Suction tube
inserted
through
cervix
Fetal
cells
Several
hours
Several
hours
Karyotyping
Slide 92
Some genetic disorders can be detected at birth by simple tests that are now routinely performed in most hospitals in the United States