Hormonal control of digestion
Secretin and CCK
Stomach
Gallbladder
Liver
+
Duodenum
of small intestine
Bile
Gastrin
Secretin
Pancreas
CCK
CCK
Key
Stimulation Inhibition
+
–
+
+
+
–
Slide 49
Pancreatic Secretions
The pancreas produces proteases trypsin and chymotrypsin, protein-digesting enzymes that are activated after entering the duodenum.
Its solution is alkaline and neutralizes the acidic chyme.
Slide 50
Bile Production by the Liver
In the small intestine, bile aids in digestion and absorption of fats. Bile emulsifies fat. This is physical NOT chemical digestion. Fat emulsification increases the surface area for chemical digestion of fats by lipases.
Bile is made in the liver and stored in the gallbladder.
Slide 51
Secretions of the Small Intestine
The epithelial lining of the duodenum, called the brush border, produces several digestive enzymes.
Enzymatic digestion is completed as peristalsis moves the chyme and digestive juices along the small intestine.
Most digestion occurs in the duodenum; the jejunum and ileum function mainly in absorption of nutrients and water.
Slide 52
The small intestine has villi and microvilli that increase the surface area for absorption. Villi and microvilli are exposed to the intestinal lumen = space / cavity.
The enormous microvillar surface area greatly increases the rate of nutrient absorption.
Slide 53
Structure of the small intestine
Muscle layers
Microvilli (brush border) at apical (lumenal) surface
Vein carrying blood to hepatic portal vein
Villi
Intestinal wall
Key
Nutrient absorption
Large circular folds
Blood capillaries
Epithelial cells
Villi
Lymph vessel
Basal surface
Lacteal
Epithelial cells
Lumen
Slide 54
Small Intestine
Muscle layers
Vein carrying blood to hepatic portal vein
Villi
Intestinal wall
Key
Nutrient absorption
Large circular folds
Slide 55
Small Intestine
Microvilli (brush border) at apical (lumenal) surface
Key
Nutrient absorption
Blood capillaries
Epithelial cells
Villi
Lymph vessel
Basal surface
Lacteal
Epithelial cells