Intermediate filaments are fibers with diameters in a middle range
Slide 71
Table 6-1
10 µm
10 µm
10 µm
Column of tubulin dimers
Tubulin dimer
Actin subunit
25 nm
7 nm
Keratin proteins
Fibrous subunit (keratins coiled together)
8–12 nm
Slide 72
Table 6-1a
10 µm
Column of tubulin dimers
Tubulin dimer
25 nm
Slide 73
Table 6-1b
Actin subunit
10 µm
7 nm
Slide 74
Table 6-1c
5 µm
Keratin proteins
Fibrous subunit (keratins
coiled together)
8–12 nm
Slide 75
Microtubules are hollow rods about 25 nm in diameter and about 200 nm to 25 microns long
Functions of microtubules:
Shaping the cell
Guiding movement of organelles
Separating chromosomes during cell division
Slide 76
Centrosomes and Centrioles
In many cells, microtubules grow out from a centrosome near the nucleus
The centrosome is a “microtubule-organizing center”
In animal cells, the centrosome has a pair of centrioles, each with nine triplets of microtubules arranged in a ring
Slide 77
Fig. 6-22
Centrosome
Microtubule
Centrioles
0.25 µm
Longitudinal section of one centriole
Microtubules
Cross section
of the other centriole
Slide 78
Cilia and Flagella
Microtubules control the beating of cilia and flagella, locomotor appendages of some cells
Cilia and flagella differ in their beating patterns
Video: Chlamydomonas
Video: Paramecium Cilia
Slide 79
Fig. 6-23
5 µm
Direction of swimming
(a) Motion of flagella
Direction of organism’s movement
Power stroke
Recovery stroke
(b) Motion of cilia
15 µm
Slide 80
Cilia and flagella share a common ultrastructure:
A core of microtubules sheathed by the plasma membrane
A basal body that anchors the cilium or flagellum
A motor protein called dynein, which drives the bending movements of a cilium or flagellum
Animation: Cilia and Flagella