Enzyme shape distorts or it changes other factors to make the reaction happen
Slide 11
In a ‘natural’ reaction the product has a lower energy than the substrate so equilibrium will take it in the direction of the product.
However there is an energy ‘barrier’ to be overcome
Enzymes lower the activation energy required to bring about a reaction.
EG catalase reduces the activation energy for the reduction of H202 86-fold
Slide 12
Slide 13
Reaction rate factors
Substrate concentration
Initially rate increases with substrate conc.