DNA. Structure and Replication

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1

Slide 1

DNA

Structure

and

Replication

Slide 2

Transformation: Robert Griffith (1928)

Slide 3

DNA is the Transformer: Avery (1944)

Slide 4

Chromosomes and DNA

Slide 5

DNA has 4 Bases

Slide 6

Four DNA Bases

Adenine

Thymine

Guanine

Cytosine

Slide 7

The Sugar

Deoxyribose

Slide 8

The Nucleotides

A

G

T

C

Slide 9

Adenine pairs with Thymine

Hydrogen

Bonding

Slide 10

Guanine pairs with Cytosine

Hydrogen

Bonding

Slide 11

DNA

Slide 12

Genes and Base Pairs: A Comparison

Slide 13

The “Central Dogma”

Slide 14

Possible Modes of DNA Replication

Slide 15

Replication: 5’ to 3’ Direction ONLY

Continuous replication

on one strand

Discontinuous replication

on one strand

Slide 16

DNA Replication is Catalyzed by Enzymes

Slide 17

DNA Polymerase Adds Complementary Bases

Slide 18

DNA Polymerase Sees Errors

Slide 19

DNA Polymerase Repairs Errors