Ca2+
Ca2+
Ca2+
Ca2+
Slide 21
Ca2+
Ca2+
Ca2+
Ca2+
the myosin heads change position to achieve a lower energy state and slide the actin filaments past the stationary myosin
Slide 22
Ca2+
Ca2+
Ca2+
Ca2+
Slide 23
Ca2+
Ca2+
Ca2+
Ca2+
Slide 24
Ca2+
Ca2+
Ca2+
Ca2+
ATP binds to the bulbous heads and causes it to become detached
Slide 25
Ca2+
Ca2+
Ca2+
Ca2+
ATP binds to the bulbous heads and causes it to become detached
Slide 26
Ca2+
Ca2+
Ca2+
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
hydrolysis of ATP provides the energy to “re-cock” the heads
Slide 27
Ca2+
Ca2+
Ca2+
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
hydrolysis of ATP provides the energy to “re-cock” the heads
Slide 28
Ca2+
Ca2+
Ca2+
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
Slide 29
Ca2+
Ca2+
Ca2+
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
calcium ions are re-absorbed back into the T system
Slide 30
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
calcium ions are re-absorbed back into the T system
Slide 31
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
the troponin reverts to its normal shape and the tropomyosin move back to block the myosin binding sites
Slide 32
Ca2+
A
Pi
Pi
Pi
A
Pi
Pi
Pi
A
Pi
Pi
Pi
the troponin reverts to its normal shape and the tropomyosin move back to block the myosin binding sites
Slide 33