The Drugs Revolution and the Development of Penicillin

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Slide 1

The Drugs Revolution and the Development of Penicillin

Slide 2

Prevention and Cure

Prevention

Germ theory

Vaccinations

Smallpox

1906 Tuberculosis

1913 Diphtheria

Cure

Koch discovered that he could stain bacteria

Development of ‘magic bullets’

For example - Salvarsan 606 and Prontosil

Slide 3

Penicillin

1928 – Alexander Fleming discovers mould which kills germs – penicillin.

1929 – Fleming publishes an article on penicillin.

Slide 4

Chain and Florey

1937 – Chain and Florey do research on penicillin.

1940 – Experiment on mice.

1941 – successful tests on humans.

Slide 5

Factors

Slide 6

Government

1939 - British government fund Florey’s research

1942 – U.S. government fund production of penicillin.

1944 – mass production

Slide 7

Individuals

Alexander Fleming

Howard Florey

Ernst Chain

Research Teams

Slide 8

War

German bombing stopped Florey and Chain being able to mass produce penicillin in Britain.

America was not interested in penicillin until she entered the war in 1941.

1945 American Army using 2 million doses of penicillin a month.

Slide 9

Other Factors

Technology

Scientific experiment

Industry

Communications

Chance